An Efficient and Facile Synthesis of Capsaicin??Like Compounds as Agonists of the TRPV1 Receptor

…, BD Roufogalis, CC Duke

Index: Van Tran; Roufogalis, Basil D.; Duke, Colin G. Australian Journal of Chemistry, 1997 , vol. 50, # 7 p. 747 - 750

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Citation Number: 6

Abstract

Abstract A new versatile synthetic route is described for the preparation of capsaicin-like molecules which contain an α-hydroxy ketone functional group mimicking the amide functional group in the capsaicin structure. The key reaction in this synthesis was the