1, 4-Cyclohexanecarboxylates: potent and selective inhibitors of phosophodiesterase 4 for the treatment of asthma

SB Christensen, A Guider, CJ Forster…

Index: Journal of Medicinal Chemistry, , vol. 41, # 6 p. 821 - 835

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Citation Number: 147

Abstract

... Journal of Medicinal Chemistry. ... Results and Discussion. Chemistry. Rolipram was synthesized and resolved as described previously. 53 Independent treatment of (R)- and (S)-rolipram with sodium hydride in anhydrous ...

1, 4-Cyclohexanecarboxylates: potent and selective inhibitor...

[Christensen, Siegfried B.; Guider, Aimee; Forster, Cornelia J.; Gleason, John G.; Bender, Paul E.; Karpinski, Joseph M.; Dewolf Jr., Walter E.; Barnette, Mary S.; Underwood, David C.; Griswold, Don E.; Cieslinski, Lenora B.; Burman, Miriam; Bochnowicz, Steven; Osborn, Ruth R.; Manning, Carol D.; Grous, Marilyn; Hillegas, Leonard M.; Bartus, Joan O'Leary; Dominic Ryan; Eggleston, Drake S.; Curtis Haltiwanger; Torphy, Theodore J. Journal of Medicinal Chemistry, 1998 , vol. 41, # 6 p. 821 - 835]

Rearrangement of epoxynitriles: A convenient homologation of...

[Journal of Organic Chemistry, , vol. 67, # 15 p. 5440 - 5443]