Abstract: Amino group of thiazole (SMB-1) have been treated with various aromatic aldehydes to get corresponding Schiff bases (SMB-2 to SMB-9). These Schiff bases have been then reacted with chloroacetyl chloride to get corresponding azetidinones (SMB-2a to SMB-9a). The structures of all these compounds have been established on the basis of analytical and spectral data. Compounds SMB-1, SMB-2 and SMB-6 are comparable with ...