Synthesis of 1, 3-diketones using. alpha.-diazo ketones and aldehydes in the presence of tin (II) chloride

A Padwa, SF Hornbuckle, Z Zhang…

Index: Padwa, Albert; Hornbuckle, Susan F.; Zhang, Zhijia; Zhi, Lin Journal of Organic Chemistry, 1990 , vol. 55, # 18 p. 5297 - 5299

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Citation Number: 70

Abstract

Recent publications from our laboratory have introduced a new general strategy for oxapolycyclic ring synthesis in which a rhodium (I1)-catalyzed tandem cyclization- cycloaddition reaction represents the central element.'For ongoing studies to further implement and develop this strategy, we required a general route to a-diazo 1, 3-diketones, which serve as the precursors for carbonyl ylide dipoles of type 2. Highly stabilized 6- ...