The Journal of organic chemistry

Click-Reagent Version of Sonogashira Coupling Protocol to Conjugated Fluorescent Alkynes with No or Reduced Homocoupling

SS Bag, R Kundu, M Das

Index: Bag, Subhendu Sekhar; Kundu, Rajen; Das, Manas Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 2332 - 2337

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Citation Number: 12

Abstract

A click-reagent version of the Sonogashira-coupling protocol has been developed. Diarylalkynes with donor and/or acceptor substituents have been synthesized via this protocol at moderate to excellent yields and with no or drastically reduced quantities of undesired homocoupled side products. This protocol is green-solvent compatible, air- insensitive, and effective under microwave conditions.