The first synthesis of 6-phenyl-2, 6-diazabicyclo [3.2. 0] heptane 1 and its orthogonally protected precursor 2 is herein reported. Our strategy enables to chemically address the two nitrogen atoms of 2, 6-diazabicyclo [3.2. 0] heptane core individually and selectively, thus allowing rapid access to several subsets of widely substituted fused azetidines.
