Thioamides are an interesting class of organic compounds which have been utilized in a variety of synthetic transformations,'including several methods for the selective reduction of amides to amines. 2 A thioamide is normally prepared by refluxing the corresponding amide with excess P4Sl0 in various solvents.'Since the reaction is heterogeneous in nature, it usually requires a large excess of P4S10 and it must be carried out for prolonged times. ...
