Abstract O-Alkylation at the anomeric centre of the dianion of 4, 5: 7, 8-di-O-cyclohexylidene- 3-deoxy-N-methyl-α-d-manno-octulopyranosonamide (1) with several triflates led diastereoselectively to the α-glycosides. In this way, lipopolysaccharide building-blocks containing α-Kdo-(2→ 6)-GlcN and α-Kdo-(2→ 6)-β-GlcN-(1→ 6)-GlcN moieties were obtained and deployed in the synthesis of decyl 4, 5, 7, 8-tetra-O-acetyl-3-deoxy-N-methyl ...
