Abstract: A new synthetic method for the preparation of amines is reported (Scheme I). Allylic alcohols are condensed with trichloroacetonitrile to yield the corresponding allylic trichloroacetimidic esters (3). Thermolysis of 3 at 25-140 OC results in allylic rearrangement to afford the corresponding trichloroacetamide 4. To complete the l, 3 conversion of a hydroxy to a primary amino group, the trichloroacetyl group can be removed by treatment ...
