Successive replacement of halogen atoms in 4, 6-dihaloquinolines in cross-coupling reactions with arylboronic acids catalyzed by palladium and nickel complexes

IP Beletskaya, AV Tsvetkov, GV Latyshev…

Index: Beletskaya; Tsvetkov; Latyshev; Lukashev Russian Journal of Organic Chemistry, 2003 , vol. 39, # 11 p. 1660 - 1667

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Citation Number: 16

Abstract

Abstract Conditions were found where in 6-halo-4-quinolines (halogen= iodine, bromine, or chlorine) the halogen atoms were replaced in succession by similar or different aryl groups in cross-coupling reactions with arylboric acids catalyzed by palladium and nickel complexes. Basing on successive Suzuki reaction a convenient procedure was developed for preparation of diarylquinolines that did not require isolation of the intermediate ...