Synthesis and structure of 6??exo??hydroxy??1, 2??diphenyl??1??phosphoniatricyclo [3.3. 1.1] decane iodide, a derivative of 1??phosphaadamantane

HJ Meeuwissen, G Sirks, F Bickelhaupt…

Index: Meeuwissen, H. J.; Sirks, G.; Bickelhaupt, F.; Stam, C. H.; Spek, A. L. Recueil: Journal of the Royal Netherlands Chemical Society, 1982 , vol. 101, # 12 p. 443 - 450

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Citation Number: 4

Abstract

Abstract The annelation reaction between l, 2, 3, 6-tetrahydro-1-phenyl-4-(1-pyrrolidinyl) phosphorin 1-oxide (10) and 2, 2-bis (chloromethyl) acetophenone (7) leads to two stereoisomeric 7-benzoyl-3-phenyl-3-phosphabicyclo [3.3. 1] nonan-9-one 3-oxides 11a and 11b. Their difference resides in the configuration at phosphorus, which also determines the conformation of the bicyclononane skeleton, as revealed from the crystal structures. ...