A series of N′-[3, 4-disubstituted-1, 3-thiazol-2 (3H)-ylidene]-2-(pyrazin-2-yloxy) acetohydrazide 11–66 and N′-[(2Z)-3-(4-bromophenyl)-4-oxo-1, 3-thiazolidin-2-ylidene]-2- (pyrazin-2-yloxy) acetohydrazide 68–74 were synthesized using appropriate synthetic route. The entire test compounds 11–66 and 68–74 were assayed in vitro for antibacterial activity against two different strains of Gram-negative (E. coli and S. typhi), Gram-positive (S. ...
