Tetrahedron

Palladium-catalyzed Suzuki–Miyaura cross-coupling reaction of potassium 2-pyridyl trifluoroborate with aryl (heteroaryl) halides

W Ren, J Li, D Zou, Y Wu, Y Wu

Index: Ren, Wei; Li, Jingya; Zou, Dapeng; Wu, Yangjie; Wu, Yusheng Tetrahedron, 2012 , vol. 68, # 5 p. 1351 - 1358

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Citation Number: 24

Abstract

Palladium-catalyzed Suzuki–Miyaura cross-coupling reaction of potassium pyridine-2- trifluoroborates and various aryl (heteroaryl) halides can generate the corresponding desired coupling products with moderate to good yields. It can be carried out under the conditions with ethanol as solvent, Pd (OAc) 2 and SPhos as catalyst system and Na2CO3 as a base.