... Median effective dose (EDSU) was calculated accord— ing to Weil's method.” Neurotoxicityl'” Neurotoxicity was defined as inability of the animals to remain on a horizontal rod (3.4cm) rotating at 5 rpm. ... 4) R. Iemura, M. Hori. T. Saito and H. Ohtaka, Chem. Pharm. ...