Optical resolution of racemic 4-hydroxy-3-isobornyl-5-methylbenzaldehyde

EV Buravlev, IY Chukicheva, AV Churakov…

Index: Buravlev; Yu Chukicheva; Churakov; Kutchin Russian Journal of Organic Chemistry, 2012 , vol. 48, # 1 p. 64 - 68

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Abstract

Abstract Racemic 4-hydroxy-3-isobornyl-5-methylbenzaldehyde was separated into particular enantiomers via transformation into diastereoisomeric Schiff bases by reaction with (R)-1-phenylethanamine. The absolute configuration of the products was determined on the basis of the X-ray diffraction data for camphanate derived from one enantiomer of 4- hydroxy-3-isobornyl-5-methylbenzaldehyde.