Journal of organometallic chemistry

Analysis of the enantioselectivities and initial rates of the hydrosilylation of acetophenone catalyzed by [Rh (cod) Cl] 2/(chiral diphosphine). The quantitative analysis of …

C Reyes, A Prock, WP Giering

Index: Reyes, Clementina; Prock, Alfred; Giering, Warren P. Journal of Organometallic Chemistry, 2003 , vol. 671, # 1-2 p. 13 - 26

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Citation Number: 21

Abstract

Through the application of the quantitative analysis of ligand effects (QALE) method to the study of the hydrosilylation of acetophenone, we have shown, for the first time, that the initial rate and enantioselectivity of a complicated catalytic system responds in a rational manner to the variations in the stereoelectronic properties of the silane. The reactions (in benzene- d6 at 63° C) were catalyzed by [Rh (cod) Cl] 2/(chiral diphosphine)(chiral diphosphine=(R) ...