Antiviral research

Effect of N-methylisatin-β-4′: 4′-diethylthiosemicarbazone on intracellular Moloney leukemia virus constituents

D Ronen, E Nir, Y Teitz

Index: Edelstein; Avramoff; Shtacher; Teitz European Journal of Medicinal Chemistry, 1980 , vol. 15, # 6 p. 566 - 566

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Citation Number: 16

Abstract

Abstract N-Methylisatin-β-4′: 4′-diethylthiosemicarbazone (M-IBDET) inhibits intracellular production of viral constituents in a mouse cell line, 3T3/MLV, chronically infected with Moloney leukemia virus. Electron microscopic observations confirmed that inhibition of virus