Tetrahedron

A recyclable Cu-catalyzed C–N coupling reaction in water and its application to synthesis of imidazo [1, 2-a] quinoxaline

L Huang, R Yu, X Zhu, Y Wan

Index: Huang, Liye; Yu, Ruina; Zhu, Xinhai; Wan, Yiqian Tetrahedron, 2013 , vol. 69, # 42 p. 8974 - 8977

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Citation Number: 14

Abstract

Abstract Polystyrene-supported pyrrole-2-carbohydrazide (PSP) was synthesized and combined with CuI to make up a recyclable heterogeneous catalytic system for Ullmann-type C–N coupling reaction in water. In which, a variety of functionalized aryl halides animated efficiently with anilines, benzylamine, aliphatic amines, and imidazole. its preliminary application resulted in a more practical synthesis of imidazo [1, 2-a] quinoxaline.