Conjugation of Arg-Gly-Asp (RGD) sequence in copolymer bearing sugar moiety for insulinoma cell line (MIN6) culture

K Na, HK Choi, T Akaike, KH Park

Index: Kun, Na; Choi, Hoo-Kyun; Akaike, Toshihiro; Park, Keun-Hong Bioscience, Biotechnology and Biochemistry, 2001 , vol. 65, # 6 p. 1284 - 1289

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Citation Number: 9

Abstract

Copolymers composed of an Arg-Gly-Asp (RGD) sequence for the adhesion molecule and sugar moieties were synthesized for an insulinoma cell (MIN6) culture. MIN6 cells attached on the poly (Np-vinylbenzyl-D-maltonamide-co-6-(p-vinylbenzamido)-hexanoic acid-g- GRGDS)(p (VMA-co-VBGRGDS))-coated dishes were in a more aggregated form than other polymer-coated surfaces. P (VMA-co-VBGRGDS) also shows faster proliferation of MIN6 ...