Synthesis of new sterically hindered anilines

…, S Georgakopoulos, M Micha??Screttas…

Index: Steele, Barry R.; Georgakopoulos, Spyros; Micha-Screttas, Maria; Screttas, Constantinos G. European Journal of Organic Chemistry, 2007 , # 19 p. 3091 - 3094

Full Text: HTML

Citation Number: 6

Abstract

Abstract Ring-alkylated primary, secondary and tertiary anilines have been ethylated with ethylene at benzylic positions in a simple and inexpensive one-pot procedure which is mediated bythe use of the superbase system nBuLi/LiK (OCH 2 CH 2 NMe 2) 2 in the presence of Mg (OCH 2 CH 2 OEt) 2. Primary and secondary anilines are ethylated readily at ortho-benzylic positions but with difficulty or not at all at other positions. Tertiaryanilines ...