Tetrahedron letters

1, 8-diazabicyclo [5.4. 0] undec-7-ene (dbu): An effective base for the introduction of t butyldimethylsilyl group in organic compounds.

JM Aizpurua, C Palomo

Index: Aizpurua, Jesus M.; Palomo, Claudio Tetrahedron Letters, 1985 , vol. 26, # 4 p. 475 - 476

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Citation Number: 69

Abstract

Abstract Reaction of alcohols, thiols, amines, carboxylic acids, phenols, hydroquinones, ketoesters and amides with equimolecular amounts of t-butyldimethylchlorosilane and DBU, even in solvents other than dimethylformamide affords the corresponding t-butyldimethylsilyl derivatives in high yield.