During the last few decades, a central aim in synthetic organic chemistry has been to provide greener and more economically viable processes for the efficient synthesis of biologically active compounds with potential application in the pharmaceutical or agrochemical industries. One approach to this goal is to design reactions using solvent-free condition 11. (a) Tanaka, K.; Toda, F. Chem. Rev. 2000, 100, 1025–1074; (b) Martins, MAP; Frizzo, CP; Moreira, DN; ...
