e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Novel thrombin inhibitors incorporating weakly basic heterobicyclic P 1-arginine mimetics: optimization via modification of P 1 and P 3 moieties

A Kranjc, L Peterlin-Mašič, J Ilaš, A Preželj…

Index: Bioorg. Med. Chem. Lett., , vol. 14, # 12 p. 3251 - 3256

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Citation Number: 10

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... b Lek Pharmaceuticals dd, Drug Discovery, Verovškova 57, 1526 Ljubljana, Slovenia; c University Medical Centre, Department of Angiology, Zaloška 7, 1525 Ljubljana, Slovenia. ...

4,5,6,7-TETRAHYDRO-2,6-BENZOTHIAZOLE DIAMINE Structure

4,5,6,7-TETRAHY...

~%

(+)-(6R)-2,6-diamino-4,5,6,7-tetrahydrobenzothiazole Structure

(+)-(6R)-2,6-di...

(S)-4,5,6,7-Tetrahydro-2,6-benzothiazolediamine Structure

(S)-4,5,6,7-Tet...

4,5,6,7-TETRAHYDRO-2,6-BENZOTHIAZOLE DIAMINE Structure

4,5,6,7-TETRAHY...

~%

(+)-(6R)-2,6-diamino-4,5,6,7-tetrahydrobenzothiazole Structure

(+)-(6R)-2,6-di...

(S)-4,5,6,7-Tetrahydro-2,6-benzothiazolediamine Structure

(S)-4,5,6,7-Tet...

Dopamine autoreceptor agonists: resolution and pharmacologic...

[Journal of Medicinal Chemistry, , vol. 30, # 3 p. 494 - 498]

Synthesis and identification of a new class of (S)-2, 6-diam...

[Investigational New Drugs, , vol. 28, # 4 p. 454 - 465]

Synthesis and identification of a new class of (S)-2, 6-diam...

[Investigational New Drugs, , vol. 28, # 4 p. 454 - 465]