Tetrahedron letters

Fluoride-mediated phosphination of alkenes and alkynes by silylphosphines

M Hayashi, Y Matsuura, Y Watanabe

Index: Hayashi, Minoru; Matsuura, Yutaka; Watanabe, Yutaka Tetrahedron Letters, 2004 , vol. 45, # 50 p. 9167 - 9169

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Citation Number: 29

Abstract

Regioselective phosphination of carbon–carbon unsaturated bonds by a fluoride-mediated reaction of silylphosphines is described. Alkenes and alkynes having a directing group, such as an aromatic or a carbonyl group, reacted to form a carbon–phosphorus bond under mild conditions. When an anhydrous fluoride source was applied in the presence of an electrophile, the corresponding three-component coupling product was obtained.