Biosynthesis of iso-fatty acids in myxobacteria

JS Dickschat, HB Bode, RM Kroppenstedt…

Index: Dickschat, Jeroen S.; Bode, Helge B.; Kroppenstedt, Reiner M.; Mueller, Rolf; Schulz, Stefan Organic and Biomolecular Chemistry, 2005 , vol. 3, # 15 p. 2824 - 2831

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Citation Number: 38

Abstract

The fatty acid (FA) profiles of the myxobacteria Stigmatella aurantiaca and Myxococcus xanthus were investigated by acidic methanolysis of total cell extracts and GC or GC-MS analysis. The main components were 13-methyltetradecanoic acid (iso-15: 0) and (Z)- hexadec-11-enoic acid (16: 1, ω-5 cis). The biosynthesis of iso-FAs was investigated in several feeding experiments. Feeding of isovaleric acid (IVA) to a mutant impaired in the ...