Chemical communications

Nickel-catalyzed cocyclotrimerization of arynes with diynes; a novel method for synthesis of naphthalene derivatives

JC Hsieh, CH Cheng

Index: Hsieh, Jen-Chieh; Cheng, Chien-Hong Chemical Communications, 2005 , # 19 p. 2459 - 2461

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Citation Number: 26

Abstract

The NiBr2 (dppe)–Zn system effectively catalyzes the [2+ 2+ 2] cocyclotrimerization of arynes with diynes, leading to substituted naphthalene derivatives in moderate to good yields. This cocyclotrimerization reaction shows excellent tolerance of functional groups and leads to products of 5-to 7-membered fused-ring sizes