Synthesis of isomeric 2-oxazolidinones from (1R, 2R)-and (1S, 2S)-2-amino-1-(4-nitrophenyl)-1, 3-propanediols

M Madesclaire, VP Zaitsev, JV Zaitseva…

Index: Madesclaire; Zaitsev; Zaitseva; Sharipova Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 10 p. 1325 - 1332

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Citation Number: 3

Abstract

Abstract A synthesis is reported for (4 R, 5 R)-and (4 S, 5 S)-4-hydroxymethyl-5-(4- nitrophenyl) oxazolidin-2-ones and (1′ R, 4 R)-and (1′ S, 4 S)-4-[hydroxy (4-nitrophenyl) methyl] oxazolidin-2-ones from (1 R, 2 R)-and (1 S, 2 S)-2-amino-1-(4-nitrophenyl)-1, 3- propanediols. The effect of the experimental conditions on the formation of these compounds was studied.