Tetrahedron Letters

An expeditious, bidirectional synthesis of furofuranones: a new application of Morita–Baylis–Hillman adducts

G Mehta, BA Bhat, THS Kumara

Index: Mehta, Goverdhan; Bhat, Ahmad Bilal; Kumara, T. H. Suresha Tetrahedron Letters, 2009 , vol. 50, # 47 p. 6597 - 6600

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Citation Number: 20

Abstract

A concise, flexible approach of general utility to the furo [3, 2-b] furanones from readily available Morita–Baylis–Hillman adducts is delineated. In an expeditious variant of this approach, a four-step cascade process is executed in a one-pot operation to generate the furofuranoid framework containing two quaternary centers.