Molecules

Synthesis of 2RS, 4RS-1-[2-phenyl-4-[2-(2-trifluromethoxy-phenoxy)-ethyl]-1, 3-dioxolan-2-yl-methyl]-1H-1, 2, 4-triazole derivatives as potent inhibitors of …

K Yamada, Y Yoshizawa, K Oh

Index: Yamada, Kazuhiro; Yoshizawa, Yuko; Oh, Keimei Molecules, 2012 , vol. 17, # 4 p. 4460 - 4473

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Citation Number: 24

Abstract

Abstract: Brassinosteroids are important phytohormones that affect many aspects of plant growth and development. In order to manipulate brassinosteroid levels in plant tissues by using specific biosynthesis inhibitors, we have carried out a systemic search for specific inhibitors of brassinosteroid biosynthesis. Synthesis of triazole derivatives based on the ketoconazole scaffold revealed a series of novel brassinosteroid biosynthesis inhibitors ( ...