Abstract Six secondary N-hydroxy amino acids (amavadin-based ligands) have been prepared through a strategy with nitrone reduction as its key step. Two of these amino acids are the new amavadin ligand analogues 4a and 4b containing either a phenyl or a benzyl group in combination with a small backbone substituent. In addition, the monoester 5 of the amavadin ligand as well as three N-alkylated N-hydroxy aminoacids 6 were prepared. ...
![2-[carboxymethyl(hydroxy)amino]acetic acid Structure](https://image.chemsrc.com/caspic/453/87339-38-6.png)