The mechanistic toxicology of isoprene is a subject of considerable current importance. 1 In this context, samples of single enantiomers of isoprene epoxides are required for the preparation of reference standards of DNA adducts. We describe efficient syntheses of enantiomerically pure (S)-2-ethenyl-2-methyloxirane 1 and (2R,2′S)-2-methylbioxirane 2, using as starting material the 'dispoke protected lactate' 3 derived from (S)-lactic acid. 2 An eight-step synthesis of ...
![(6R,7R,15S)-15-methyl-15-vinyl-1,8,13,16-tetraoxadispiro[5.0.57.46]hexadecan-14-one Structure](https://image.chemsrc.com/caspic/092/292177-94-7.png)