Regio??and Chemoselective Coupling of Polyalkynes: A Convenient Access to Polyarylacetylenes and Polyenynes

U Halbes??Létinois, A Vasiliev…

Index: Halbes-Letinois, Ulla; Vasiliev, Aleksander; Pale, Patrick European Journal of Organic Chemistry, 2005 , # 13 p. 2828 - 2834

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Citation Number: 5

Abstract

Abstract Mono-or disilylated α, ω-diynes and disilylated triynes can be regioselectively homologated at each acetylenic end, silylated or not, by two and three, respectively, successive Pd/Ag-catalyzed coupling reactions. Each coupling being selective either for terminal alkyne, trimethylsilylalkyne or for trialkylsilylalkyne, the combination of these coupling methods offers a unique and rapid access to polyunsaturated compounds.(© ...