A convenient synthesis of some Pyrazolinone and Pyrazole derivatives

…, MA Abdo, AA El??Gharably

Index: Aly, El-Saied A.; Abdo, Mohamed A.; El-Gharably, Atif A. Journal of the Chinese Chemical Society, 2004 , vol. 51, # 5 A p. 983 - 990

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Citation Number: 13

Abstract

Abstract A convenient synthesis of some novel 6-amino-4-aryl-1-phenyl-3-pyridin-4-yl-1, 4- dihydropyrano [2, 3-c] pyrazole-5-carbonitriles (3a, b) and 5-chloro-1-phenyl-3-pyridin-4-yl- 1H-pyrazole-4-carbaldehyde (4) is described. Compound 4 was obtained by the reaction of 2-phenyl-5-pyridin-4-yl-2, 4-dihydropyrazol-3-one (1) with dimethylformamide and phosphorus oxychloride under Vilsmeier-Haack reaction conditions. Compound 4 was ...