... 1997, 35, 712. (6) Brandsma, L. Preparative Acetylenic Chemistry; Elsevier: Am- sterdam, 1988; p 63. (7) Aerssens, MHPJ; Van der Heiden, R.; Heus, M.; Brandsma, L. Synth. ... Notes J. Org. Chem., Vol. ... 5, 2000 1559 Page 3. yn-1-ols should be very important in organic synthesis. ...