Chiral allenylboronic esters: A practical reagent for enantioselective carbon-carbon bond formation

…, M Ishiguro, N Ikeda, H Yamamoto

Index: Haruta, Ryuichi; Ishiguro, Masaharu; Ikeda, Nobuo; Yamamoto, Hisashi Journal of the American Chemical Society, 1982 , vol. 104, # 26 p. 7667 - 7669

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Citation Number: 106

Abstract

1)(+)-Dialkyl tartrate bar and two dropping funnels, was dried and flushed with nitrogen. The flask was charged with 300 mL of dry ether and cooled by stirring in a-78" C bath. Freshly distilled trimethyl borate (26 mL, 220 mmol) was charged in the funnel. Freshly prepared propargylmagnesium bromide (ca. 1 M in ether, 200 mm~ l)~ was pressure-transferred to the other funnel. Two reactants were added to the vigorously stirred reaction mixture at-78" C ...