Organic letters

Highly Regioselective Anti-Markovnikov Palladium-Borate-Catalyzed Methoxycarbonylation Reactions: Unprecedented Results for Aryl Olefins

TO Vieira, MJ Green, H Alper

Index: Vieira, Tiago O.; Green, Mike J.; Alper, Howard Organic Letters, 2006 , vol. 8, # 26 p. 6143 - 6145

Full Text: HTML

Citation Number: 37

Abstract

A general, highly efficient and regioselective methoxycarbonylation, by means of a palladium-salicylicborate-catalyzed protocol, of terminal alkyl and aryl olefins is described. The substrates include aliphatic alkenes, allylbenzenes, and styrene derivatives. The yields are very good (60-92%) and the regioselectivity, in favor of the linear ester, is up to quantitative unprecedented in the case of styrenes.