Journal of heterocyclic chemistry

Dihydropyrimidines and related structures. I. N2??substituted 2??pyrimidinamines and dihydro??2??pyrimidinamines by reaction of phenylbutenones and monosubstituted …

W Wendelin, K Schermanz

Index: Wendelin, Winfried; Schermanz, Karl Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 1 p. 65 - 69

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Citation Number: 21

Abstract

Abstract The reactions of monosubstituted guanidines 2 with phenylbutenones 7 and 10 exclusively yield N 2-substituted 2-pyrimidinamines 8 and 9. The structure of the reaction products is proved and their differing stability is discussed. Action of methyl-and benzylguanidine respectively (2b, c) on 4-phenyl-3-buten-2-one (7) and of 2c on l-phenyl-2- buten-1-one (10) under atmospheric oxygen affords aromatic N 2-substituted 2- ...