Intramolecular Ritter Reactions of 2??(2??Cyanoethyl) tetrahydrocyclopenta [b] indole and??carbazole Derivatives

…, A Van den Bogaert, F Compernolle…

Index: Maertens, Faye; Van Den Bogaert, An; Compernolle, Frans; Hoornaert, Georges J. European Journal of Organic Chemistry, 2004 , # 22 p. 4648 - 4656

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Citation Number: 15

Abstract

Abstract Intramolecular Ritter reactions of 2-(2-cyanoethyl) tetrahydrocyclopenta [b] indole and-carbazole derivatives, prepared by a sequence of two different α-substitutions and Grignard reactions of the indole-based ketones 4-methyl-1, 4-dihydrocyclopenta [b] indol-3 (2H)-one and 9-methyl-2, 3, 4, 9-tetrahydro-1H-carbazol-1-one, were used as key steps in the construction of various tetracyclic lactam compounds.(© Wiley-VCH Verlag GmbH & ...