Acta poloniae pharmaceutica

Synthesis, physico-chemical and anticonvulsant properties of some N-substituted amides of 3-spirocycloalkylpyrrolidine-2, 5-dione

J Obniska, A Zejc

Index: Obniska, Jolanta; Zejc, Alfred Acta Poloniae Pharmaceutica - Drug Research, 2003 , vol. 60, # 5 p. 383 - 390

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Citation Number: 8

Abstract

Abstract: The synthesis and physicochemical properties of new derivatives of N-ben/yl and N- phenyl amides of 2-(3-spirocyclohexanepyrrolidine-2, 5-dione) acetic acid, 4-(3- spirocyciohexanepyrrolidine-2, 5-dione) benzoic acid and 4—(3- spirocyclopentanepyrrolidine-2, 5-dione) benzoic acid are described. N-substituted amides were prepared by condensing the obtained acids with the corresponding phenyl-or ...