Synthesis and Antimuscarinic Properties of Quinuclidin-3-yl 1, 2, 3, 4-Tetrahydroisoquinoline-2-carboxylate Derivatives as Novel Muscarinic Receptor Antagonists 1

R Naito, Y Yonetoku, Y Okamoto…

Index: Tikk, Istvan; Deak, Gyula; Toth, Gabor; Tamas, Jozsef Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 4 p. 619 - 623

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Citation Number: 70

Abstract

... Journal of Medicinal ... J. Med. Chem. , 2005, 48 (21), pp 6597–6606. DOI: 10.1021/jm050099q. Publication Date (Web): September 28, 2005. Copyright © 2005 American Chemical Society. ... 28), 13 and 4-hydroxy-1-phenyl-1,2,3,4-tetrahydroisoquinolines (cis-29 and trans-29), 20 ...