Butyllithium addition to 2-fluoropyridine occurs at low temperature. Hydrolysis of the resulting reaction mixture leads to an adduct, the structure of which is shown to be 2-butyl-6- fluoro-2, 5-dihydropyridine. This result was chemically proved and conformed by'H and 13C NMR spectroscopy (we establish, moreover, some physicochemical properties of this structure, IR, UV, etc.). The 2-fluoropyridine-butyllithium adduct reacts with various alkyl ...
