Azide photoaffinity analogs for acridine dye binding sites

DM Mueller, RA Hudson, CP Lee

Index: Mueller, David M.; Hudson, Richard A.; Lee, Chuan-pu Journal of the American Chemical Society, 1981 , vol. 103, # 7 p. 1860 - 1862

Full Text: HTML

Citation Number: 7

Abstract

Figure 1. Synthesis of 3-azido-9-[[C (diethylamino)-1-methylbutyl] amino]-7-methoxyacridine. associated with the generation of a proton gradient. Also, quinacrine bound to the local anesthetic site of the nicotinic acetylcholine ionophore in membrane vesicles from the electric organ of Torpedo marmorata has provided a fluorescent probe useful in the analysis of the coupling of the ionophore with the acetylcholine receptor system. l1ll2 In addition to ...