Journal of medicinal chemistry

Radioprotective thiazolidines from. beta.-keto esters

PS Farmer, CC Leung, EMK Lui

Index: Farmer,P.S. et al. Journal of Medicinal Chemistry, 1973 , vol. 16, # 4 p. 411 - 413

Full Text: HTML

Citation Number: 14

Abstract

Antiradiation activity has been reported for a variety of thiaz~ lidines,"~ although the absence of significant protection in certain other derivatives led Sweetman, et al.,'to conclude that a thiazolidine" ordinarily is likely to lock an aminothiol too firmly into a stable structure to afford a promising means of latentiating biologically active aminothiols." captoethylamine (MEA) in the form of 2, 2-disubstituted thiazolidine derivatives of some P- ...