Highly stereoselective, one-pot synthesis of azetidines and 2, 4-dioxo-1, 3-diazabicyclo [3.2. 0] compounds mediated by I2

CB Miao, CP Dong, M Zhang, WL Ren…

Index: Branch, Clive L.; Pearson, Michael J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1097 - 1100

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Citation Number: 5

Abstract

... The Journal of Organic ... J. Org. ... The cyclization of the Michael adduct α-benzamidomalonate 3aa was then selected as a model reaction (Table 1). Although the α-hydroxymalonates could be transformed to oxetanes under I 2 /Na 2 CO 3 /DMF conditions quantitatively,(13) no ...