The major diterpenes in the toxic extracts of Briareum asbestinum (Pallus) from three Honduras Bay Island collections are reported. The structures and chemistry of two new asbestinins, 2 and 3, and four known ones, 4, 5, 9, and 10, are discwed. Structures for 2 and 3 were derived from spectroscopic arguments and were confiied by chemical interconversions. NMR experiments including 13C at 90 MHz, a plot of JR/JCH with b~, ...
