Reduction of isopropylidene acylmalonates, 5-acylbarbituric acids, and 3-acyl-4-hydroxycoumarins to the corresponding alkyl derivatives by sodium …

CF Nutaitis, RA Schultz, J Obaza…

Index: Nutaitis, Charles F.; Schultz, Rose Ann; Obaza, Judy; Smith, Francis X. Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4606 - 4608

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Citation Number: 44

Abstract

Isopropylidene acylmalonates, 5-acylbarbituric acids, and 3-acyl-4-hydroxycoumarins are readily reduced to the corresponding alkyl derivatives by sodium cyanoborohydride-acetic acid. The cyclic substrates are readily prepared by the acylation of isopropylidene ...