Highly Selective Barbier??Type Propargylations and Allenylations Catalyzed by Titanocene (III)

…, I Sancho??Sanz, E Álvarez??Manzaneda…

Index: Munoz-Bascon, Juan; Sancho-Sanz, Iris; Alvarez-Manzaneda, Enrique; Rosales, Antonio; Oltra, J. Enrique Chemistry--A European Journal, 2012 , vol. 18, # 45 p. 14479 - 14486,8

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Citation Number: 21

Abstract

Abstract The alkyne functional group is found in many bioactive natural products and is the key to many important chemical transformations developed over recent years. Moreover, allenes have recently gained relevance as versatile reagents in organic synthesis. Mild, catalytic methods to enable the selective introduction of either alkyne or allene motifs into organic molecules are very valuable but, as yet, quite scarce. We describe an extremely ...