Phosphorus, Sulfur, and Silicon

Synthesis and Reactions of Some New Heterocyclic Compounds Related to Pyrrolylthieno [2, 3-d] pyrimidines and Thieno [2, 3-d][4, 5-d] dipyrimidines

MI Abdel Moneam

Index: Abdel Moneam, Maisa I. Phosphorus, Sulfur and Silicon and the Related Elements, 2005 , vol. 180, # 2 p. 375 - 388

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Citation Number: 4

Abstract

ABSTRACT Condensation of ethyl-5-amino-2, 4-diphenylthieno [2, 3-d] pyrimidine-6- carboxylate (3a) with 2, 5-dimethoxy tetrahydrofurane in acetic acid gives the corresponding 5-pyrrolyl derivative 4, which in turn could be easily reacted with hydrazine hydrate in ethanol yielding the carbohydrazide derivative 5. Reaction of 5 with aromatic aldehydes, acetylacetone, carbon disulfide or phenylisothiocyanate gave pyrrolyl derivatives 6–9 ...