Chemistry and physics of lipids

Ultrasound in fatty acid chemistry: facile dehydrobromination of dibromo fatty esters to acetylenic ester derivatives

MSFLK Jie, P Kalluri

Index: Jie, Marcel S. F. Lie Ken; Kalluri, P. Chemistry and Physics of Lipids, 1998 , vol. 91, # 1 p. 79 - 83

Full Text: HTML

Citation Number: 1

Abstract

Dehydrobromination of dibromo derivatives of olefinic fatty acids was accomplished using KOH in 20% aqueous ethanol under concomitant ultrasonic irradiation (20 kHz) for 30 min at ambient temperature to give the corresponding acetylenic fatty acid derivatives (52–72% yield). Ten different dibromo fatty acid substrates were used. Products include: fatty acids with a terminal or internal acetylenic bond; acetylenic fatty acids containing an additional ...