Tetrahedron: Asymmetry

An efficient method for the synthesis of enantiopure phosphine–imidazoline ligands: application to the Ir-catalyzed hydrogenation of imines

E Guiu, C Claver, J Benet-Buchholz, S Castillón

Index: Guiu, Ester; Claver, Carmen; Benet-Buchholz, Jordi; Castillon, Sergio Tetrahedron Asymmetry, 2004 , vol. 15, # 21 p. 3365 - 3373

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Citation Number: 60

Abstract

Phosphine–imidazoline ligands 8, and the derivatives 16 and 17, which have electron- withdrawing or electron-donating groups in the aminic nitrogen, were synthesized from 2- aryl-imidazolines, which have previously been obtained from dithioesters. The coordination of ligand 8 to Ir (I) was studied and the molecular structure of the [Ir (η4-COD) 8] BF4 (COD= 1, 5-cyclooctadiene) determined through X-ray diffraction. The in situ prepared Ir (I)/ ...